A family of Microsoft relational database management systems designed for ease of use.
Nobody is modifying in design mode.
My question is more why is this happening in the first place?
The message does not mean that anyone is opening a object in Design mode. it means that the design of an object has been changed, whether in Design mode or programatically. As John suggested, it is most likely that a filter or sort order has been changed which is part of the object's design. Once that has been done, the app is placed in a read only state.
As noted the solution is to split and give each user their own front end. So such things can be applied independently.