Hi RonaldGray_66,
This is an backscatter related issue. Our engineer is working it, please keep monitor the main thread. Once the issue is resolved, we will share the solution in there.
https://answers.microsoft.com/en-us/msoffice/forum/msoffice_o365admin-mso_other/office-365-mail-flow-backscatter/b3997119-95c4-4cb6-9753-f746b49571e3
Meanwhile, please try the following two workarounds:
1.Setup backscatter = enable, based on customer's feedback, sometimes, it doesn't work.
For Office 365 users, in Exchange admin center > protection > spam filter > edit the spam policy >advanced options, set the NDR backscatter to on. After that, these backscatter emails will be marked as spam.
2.You can create a shared mailbox and a corresponding transport rule to redirect all NDRs to this shared mailbox. Then, you can check all NDRs in the shared mailbox regularly.
Update: To identify whether you are in the same situation, please send us the complete NDR error message for analysis.
To protect the privacy, I have sent you a private message to collect the information. Click the following link to access it:
https://answers.microsoft.com/en-us/privatemessages/list
Regards,
Yang