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Hi Angela,
I suggest you restore to a previous version to see if it works. You can do this by right clicking the file > Version History > select an earlier version and click Restore. Refer to Restore a previous version of an item or file in SharePoint
If the issue still exists, to help us clarify the scenario, please provide some more information:
- Do you face this issue with a specific Excel file? Have you tried other Excel files?
- Was this file created in a previous version of Excel?
- What is the type, size and format of the file?
Regards,
Joshua