Hi Edwin,
Thank you for your reply. Please see screenshot of installed office below as requested. To answer your no 2 question, yes, I can open Excel and Word normally, but my biggest problem is that all the programs that require excel to run cannot operate. I have a CAD software and another software that use VB scripts to write to Excel however these programs are failing to access excel as mentioned before.
The reason why I also shared that I cannot open Excel via Start>Run> Type “Excel was to try and give out more information on how this issue was affecting other programs. Furthermore, another thing I noticed is that I cannot set my signature on outlook, when I click on "Signatures" to modify my signature nothing happens.
It is worth noting that my excel was working all along until one day I suspect it was after an automated update when it stopped working. In a nutshell all the Microsoft office programs appear to be affected in one way or another.
1. Below is, Screenshot of Microsoft Office installed

2. Below is, Screen short of Version of excel installed below

Regards,
Joseph