A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data
From your description, It could be some security software crash the next step.
Does issue happen on all the users? If not ,check the difference from user which works and which doesn't work. Hope it will help to find the casue.
Since we haven't enviroment at hand, it is suggested to raise a ticket to Microsoft. The support team can remote to check the issue and help you find the casue.
Please contact your admin/IT department create a support ticket via Microsoft 365 Admin Center> Support> New service request.