A Microsoft file hosting and synchronization service.
Hello, Rose Saldivar
Welcome to Microsoft Community.
I realize that you are using a personal account and have encountered a problem with enabling Autosave feature for your files on Mac. I understand how the inconvenience this may have caused.
Recently, some users have been posting in different language sections that they are experiencing a similar situation, so your question may be a hot issue.
For example:
Post in English: onedrive office 365 cannot autosave for personal account - Microsoft Community
Post in Chinese: excel word for Mac OS 没办法自动保存文件 - Microsoft Community
You can try creating a new folder in OneDrive and saving your files in this new folder. It may be a problem with specific location in OneDrive.
Note: The above method do not always work.
If it doesn't work, I suggest that you take the following method as a temporary workaround:
After finishing editing your file, manually upload the file to OneDrive online in your browser to save your changes.
At the same time, I sincerely recommend that you report this issue directly to OneDrive support to let them know about this embarrassing problem.
To contact:
Sign in to OneDrive Online, and then click this link: Email OneDrive support
Or you can click the feedback button in the top right corner and select "Report a problem."
Thank you for your understanding and cooperation.
Best wishes,
Lucia Wu - MSFT | Microsoft Community Support Specialist