Hello, Wigster2
Welcome to Microsoft Community.
I realize that you have encountered a problem that pointer frequently offset from cursor location in Office applications. I understand how you feel.
Since this problem does not happen in any other applications, it might be a problem with the Office applications itself.
Here are some steps you can try:
- Adjust the zoom percentage. You can hold down Ctrl and scroll the mouse wheel or adjust the zoom percentage in the bottom right corner of the Office application. Check if the cursor will still deviate.
- Open Office in Safe Mode. This will help identify if an add-in or extension cause this problem.
- Press the Windows + R to open the Run box.
- In the Run box, type one of these commands:
- For Excel: Type excel /safe, and click OK.
- For Outlook: Type outlook /safe, and click OK.
- For Word: Type winword /safe, and click OK.
- For PowerPoint: Typepowerpnt /safe, and click OK.
- See if the problem still exist in safe mode.
- Change mouse setting.
- Reset the Office registry. Disclaimer: Modifying registry or workgroup subkeys is generally intended for power users, administrators, and IT professionals. It can help fix some issues, however, serious problems can occur if you modify the registry incorrectly. So, make sure to follow these steps carefully. For added protection, back up the registry before modifying it. You can then restore the registry if a problem occurs. For more information about how to back up and restore the registry, click How to back up and restore the registry in Windows - Microsoft Support to view the article.
- Close all Office applications.
- Press Windows + R, in the run box that opens, type: regedit and press enter.
- Locate the following key value and rename the Office folder (right-click on it and select Rename, for example, rename Office to Officeold)
HKEY_CURRENT_USER\Software\Microsoft\Office - Then reopen Office to test the effect.
In addition, due to various reasons, we may ask you for more information.
- Office version: Open a Office (such as Word) file****> select File in the upper-left corner -> select Account. Attach a screenshot of this page.
- Windows version: Press the Windows + R, type winver in the Openbox, and then select OK.
- You mentioned that there is no such issue in the online Office. Are you opening the same file in both the online Office and the Office desktop application?
- In the Office desktop application, have you been using your laptop's touchpad as a mouse? Some users have mentioned that the touchpad can cause this issue.
Please let me know the effect of above steps. I'm looking forward to your reply. Let's take it step by step.
Best wishes,
Lucia Wu - MSFT | Microsoft Community Support Specialist