Hi @Marissa Murray,
Thank you for posting your question in the Microsoft Q&A forum.
Please notify me if I've misunderstood anything about your situation. Based on your sharing, your file is getting blocked by macros and you want to disable to open the Excel file. 1- Remove the Mark of the Web (MOTW)
- Open File Explorer, navigate to your Excel file that you need to enable macros
- Right click on it and choose Properties
- In General tab, check the Unblock box for the Security option.

- If the Unblock options is not available, it's usually because that your file is currently saved in a OneDrive or SharePoint folder and it will be considered as from the internet.
- You can try disconnecting OneDrive/SharePoint temporarily or move the file to your local folder and try the Unblock Security box again.
2- Add the file location as a trusted location
- Open Excel and go to File > Options > Trust Center > Trust Center Settings

- Select Trusted Locations in the left bane > Add new location > Browse and navigate to the folder where you keep the files need to enable macro
- Press OK to close all the dialog boxes then try opening your macro-enabled excel file again
3- Enable macros in Excel
- Open the Excel file that needs macro enabling.
- If you see a yellow warning bar at the top with the message "SECURITY WARNING: Macros have been disabled", click Enable Content to enable macro for the file
You can also adjust the trust center settings for macros by
- Go to File > Options > Trust Center > Trust Center Settings
- Click Macro Settings and choose between "Disable VBA macros with notification" (which will show a yellow warning bar as I mentioned above) and "Enable VBA macros" (only if you're sure the file is safe)
- Then click OK to save the settings
For better visualization about this guideline, you can watch this video Unblock macros downloaded from the internet | Excel Off The Grid | Microsoft macro security changes…
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Thank you for your understanding and cooperation. I'm looking forward to your reply.
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