Hi @Boopathi S ,
Please check if the status of these clients is online, about the status of client, refer to this link:
https://learn.microsoft.com/en-us/mem/configmgr/core/clients/manage/monitor-clients#bkmk_indStatus
And it seems that there are something wrong between MP and client, please run these following actions on the side of one issued client to check if any error in ScanAgent.log and CcmMessaging.log.
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