Can you be more specific? What isn't working - your app doesn't run, VS 2019 doesn't run, your app doesn't compile, what? What error(s) are you getting?
What do you mean when you got a disk letter E:? Do you mean you originally had your project on the D: drive and then you moved it to the E: drive? If so then that shouldn't matter at all unless you added hard coded (or relative paths) to something on D. Providing more information would be useful.