Hello.
First of all, please check your background processes, as they also consume memory, not just active applications. The issue may be caused by tasks running in the background.
When the CPU hits 99% during simple folder navigation, it seems struggling with real-time security scanning or background tasks that are significantly more resource-intensive in a GCCH environment. And for a stable professional experience, you should upgrade these users to a 4 vCPU / 16 GB RAM tier to provide the necessary ceiling for Microsoft 365 apps to function without constant resource contention.
If you find my answer useful, please mark it as the "Accepted Answer" so other members can find the solution easily. Your help in supporting the community is much appreciated!
Best regards,
Scott Nguyen