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If Windows is running and you would like to unlock a data (non-system) drive, this can be done using Powershell Remoting or psexec.
So you start a shell on the remote machine like this
psexec \remotepc cmd -ru adminonremote -rp adminonremotepassword
Then on the shell you go
manage-bde -unlock x: -pw
(-pw is for password protector and the password will be asked for).