The error shows a Realtek PCIe device (VEN_10EC&DEV_5287) whose driver (RTSPER, from oem61.inf) fails to start. Memory Integrity/Core isolation blocks drivers that are incompatible or not properly signed. To enable Memory Integrity, the incompatible driver must be updated or removed so that Windows no longer needs to load it.
Use these steps:
- Update or replace the device driver
- Open Device Manager.
- Expand “System devices” and “Network adapters” and look for any Realtek PCIe or unknown device with a warning icon that matches this hardware ID (right‑click → Properties → Details → “Hardware Ids” to confirm
PCI\VEN_10EC&DEV_5287). - Right‑click the device → Update driver → “Search automatically for drivers”.
- If nothing newer is found, download the latest Windows 10/11 driver for this device from the PC or motherboard vendor and install it, then restart.
- If no compatible driver exists
- In Device Manager, right‑click the problematic device → Disable device. This prevents Windows from loading the RTSPER driver.
- If the device is not needed (for example, an unused card reader or controller), it can also be uninstalled (right‑click → Uninstall device, and check “Delete the driver software for this device” if available), then restart.
- Re‑check Memory Integrity
- Open the Core isolation page in Windows Security (for example via the Core isolation link:
windowsdefender://coreisolation/). - Turn Memory Integrity On.
- Restart the computer.
- If Windows still reports an incompatible driver, note the exact driver name shown there and repeat step 1 for that driver.
- Open the Core isolation page in Windows Security (for example via the Core isolation link:
If a compatible driver cannot be obtained from the device or PC manufacturer and the device is required, Memory Integrity can be left off, but this reduces protection. On secured‑core PCs, turning off Memory Integrity also removes the secured‑core state.
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