No, it's impossible to change the default search in sharepoint for partial search. This is by design.
SharePoint search supports Keyword Query Language (KQL) syntax for building search queries. keyword-query-language-kql-syntax-reference
When you use words in a free-text KQL query, Search in SharePoint returns results based on exact matches of your words with the terms stored in the full-text index. You can use just a part of a word, from the beginning of the word, by using the wildcard operator (*) to enable prefix matching. In prefix matching, Search in SharePoint matches results with terms that contain the word followed by zero or more characters.
For example, the following KQL queries return content items that contain the terms "federated" and "search":
federated search
federat* search
search fed*
KQL queries don't support suffix matching.
So if you want to use partial strings for search , you have to use the wildcard operator (*) to enable prefix matching.