A higher Secure Kernel memory reservation is expected when VBS and Credential Guard are enabled, since they reserve memory for security features. However, a 15% drop does seem higher than usual.
You should first check whether this started after a recent Windows or HyperV update. Also monitor memory usage across all hosts to see if it's consistent or isolated to one server. If there hasn't been any recent configuration change, reviewing the Event Viewer for HyperV or VBS-related warnings would be a good next step.