Hello Devin,
The view editor for "CPU Usage (Sampled)" can be used to add a column named "Image RVA"; "Image RVA" is what you probably mean by "offset" (RVA = Relative Virtual Address).
The .etl file needs to include Image Load/Unload/Rundown events in order to calculate the "Image RVA" value.
Assuming that the .etl file contains Image Load/Unload/Rundown events, Process Create/Terminate/Rundown events and Sampled Profile events then there is no need that the "process of interest" should still be running; indeed, the trace could be analysed on another system and the RVA information would still be calculable. Including ImageId events in the trace would make converting "Image RVA" values into function (symbol) names plus offsets straightforward.
Gary