Hi @mw ,
When Developer Tools is enabled, IE doesn't really uses its HTTP cache (at least by default in IE 11) like it does in normal mode. It means if your site or page has a caching problem (if it caches more than it should for example - that was my case), you will not see that problem in F12 mode.
I refer to this thread :why-does-javascript-only-work-after-opening-developer-tools-in-ie-once
However your issue is more like IE ,you can ask on this forum for further infomation:windows-10-general.html
Best Regards,
Isabella
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