A cloud-based service included in Microsoft 365, delivering scalable messaging and collaboration features with simplified management and automatic updates.
If this sender located on Exchange on-premises, you could change the value of -RecipientRateLimit in Throttling Policy to control it.
If this sender located on Exchange online, you will cannot change it, here are limited on Exchange online send and receive.
About block reply, you could try with "Azure Information Protection(For Exchange online)" or "AD RMS Policy Template Considerations(For Exchange on-premises)"
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