It might be, that Application Control cannot be disable by design just by clicking configurations or removing them....
Application Control cannot be removed from computers

Pavel yannara Mirochnitchenko
13,166
Reputation points MVP
I quickly tested App Control and realized I cannot implement it in my enviroment. I removed the assigment of the ASR App Control Policy, but App Control is still on. This is quite funny situation:
Microsoft Intune Configuration
Microsoft Intune Configuration
Microsoft Intune: A Microsoft cloud-based management solution that offers mobile device management, mobile application management, and PC management capabilities.Configuration: The process of arranging or setting up computer systems, hardware, or software.
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Pavel yannara Mirochnitchenko 13,166 Reputation points MVP
2021-11-07T18:12:10.413+00:00 -
Rahul Jindal [MVP] 10,811 Reputation points MVP
2021-11-09T07:01:42.117+00:00 You can keep the setting in Audit mode. That way no app gets blocked and you can monitor events as well.