Have you reviewed the Security and System event logs? If UAC is failing there should be some event logged.
Build a new Win10 VM. Don't join it to your domain. Don't install any 3rd party applications. Just use local accounts to test UAC. Create 2 users, TestUser and Administrator. Log in as TestUser and verify that UAC will accept the Administrator account's credentials. Reboot, wait an hour, do whatever. Test UAC again to verify that it still works.
Then join the VM to the domain. Log in as the local TestUser and test to see if UAC still works with the local accounts.
Then log in with a domain account and see if UAC still works with the Administrator account.
If the UAC problem shows up, then sit down with your Active Directory Administrator and review the group policy settings on the VM.