Sure use the built in RBAC role and the user to the Recipient Mgmt role group
or customize it:
https://learn.microsoft.com/en-us/exchange/permissions/permissions?view=exchserver-2019
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Is it possible to grant a normal user admin access\role to one or more Exchange 2016 mailbox so that that user can manage\admin that single mailbox or some mailboxes using Exchange Admin Center?
Environment :- Exchange 2016.
Sure use the built in RBAC role and the user to the Recipient Mgmt role group
or customize it:
https://learn.microsoft.com/en-us/exchange/permissions/permissions?view=exchserver-2019
Yes, you would create a new custom scope and new custom role using that scope and assign it to a security group and put that normal admin user into that group.
Example:
New-ManagementScope -Name "Protected Exec Users" -RecipientRestrictionFilter "Title -like 'VP*'" -Exclusive
New-ManagementRoleAssignment -SecurityGroup "Executive Administrators" -Role "Mail Recipients" -CustomRecipientWriteScope "Protected Exec Users"
The RecipientRestrictionFilter would be used to filter the access to those mailboxes
What is common about the mailboxes you want the user to manage? Same Database? etc....
https://learn.microsoft.com/en-us/powershell/exchange/recipientfilter-properties?view=exchange-ps