Hi @chetan Vishwakarma ,
Yes, it is possible.
Your scenario is like below screenshot.
Azure SQL Managed Instance can support being a Subscriber from the following versions of SQL Server:
•SQL Server 2016 and later
•SQL Server 2014 RTM CU10 (12.0.4427.24) or SP1 CU3 (12.0.2556.4)
•SQL Server 2012 SP2 CU8 (11.0.5634.1) or SP3 (11.0.6020.0) or SP4 (11.0.7001.0)
There are also some other requirements for this configuration, please refer to this MS document Transactional replication with Azure SQL Managed Instance to get more information.
Please refer to below blog to get detail steps about configuration.
Standard transactional replication from on-premise SQL to Azure SQL Managed Instance
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