.net 6 did not implement app domain support, so the framework these libraries are based on does not exist. .
Loading a dll is simple
https://learn.microsoft.com/en-us/dotnet/api/system.reflection.assembly.load?view=net-6.0
And plug-in design
https://learn.microsoft.com/en-us/dotnet/core/tutorials/creating-app-with-plugin-support