If you're referring to the volume ID that is set when the drive is formatted then yes you can change it.
Download the SysInternals VolumeID tool here.
Run the tool as an admin and set the ID to what you want (ensuring it follows the format needed).
Reboot.
Note that long term it might be better to adjust your app to allow you to set the key in a different manner. Then again if you're running this in Azure and it is your app then why would you need a key to begin with.