Hi @AlexRobert ,
Here is a article "Office Online Server 2016: How to update" about how to install office online service Software Update and security patch installation. And per my research, you have to apply Office Online Server updates in specific way. Applying Office Online Server updates or new versions by using the automatic updates process isn't supported with Office Online Server. If Office Online Server updates are applied automatically, users may be unable to view or edit documents in Office Online. If this happens, you have to rebuild your Office Online Server farm. Before updating we suggest you save the current configuration and backup the whole server first.
For Reference:
Apply software updates to Office Online Server
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