Hi @Hoevenaar, Barthold ,
Yes the Office 2021 suites are supported on Windows Server 2022, you'll find this information over here:
https://www.microsoft.com/en-us/microsoft-365/microsoft-365-and-office-resources?rtc=2#coreui-heading-j4d3wac
Here's for Office Professional 2021:
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Best regards,
Leon