Nothing special really. Install the latest SSU
(2016)
https://www.catalog.update.microsoft.com/Search.aspx?q=KB5005698
followed by the latest cumulative update.
https://www.catalog.update.microsoft.com/Search.aspx?q=KB5008207
(2012 R2)
SSU
https://www.catalog.update.microsoft.com/Search.aspx?q=KB5001403
latest cumulative update
https://www.catalog.update.microsoft.com/Search.aspx?q=KB5008263
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and Accept as answer
if the reply is helpful--