Hi mortenholst-7874,
About the firewall consideration, you could refer to https://learn.microsoft.com/en-us/microsoft-365/enterprise/urls-and-ip-address-ranges?view=o365-worldwide#skype-for-business-online-and-microsoft-teams.
If you change the SIP address for the meeting organizer, either SIP username or SIP domain, MMS won’t update meetings. Organizer needs to reschedule meetings. For more details, please refer to this article:
https://learn.microsoft.com/en-us/skypeforbusiness/audio-conferencing-in-office-365/setting-up-the-meeting-migration-service-mms#updating-meetings-when-a-users-audio-conferencing-settings-change.