How about this?
set-automatic-replies-with-powershell
As an ex-email administrator this is one of the things that both annoyed me and interfered with the flow of e-mail. An uncontrolled auto-reply that sends a message to a destination that is also an uncontrolled auto-reply recipient will cause a flood of messages that will fill a mailbox (and log files, transaction logs. and mailbox database) and has the potential to degrade the ability of your system to handle normal mail.