Usually, upgrade doesn't affects activation.
Can you share us the activation message and code.
Also, try running the Activation troubleshooter, see if it helps:
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Getting Error after troubleshooting(tried multiple times)
We can't activate your copy of windows. Make sure you are connected to the internet and try again. If you are connected to the internet and continue seeing this problem, contact your system administrator for more information.
Usually, upgrade doesn't affects activation.
Can you share us the activation message and code.
Also, try running the Activation troubleshooter, see if it helps: