This article introduces more information: Configuring Anti-Spam Protection on Exchange 2013, 2016 – RBL Providers
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And in Exchange 2013, the transport role is divided into two components: Front End Transport and Back End Transport, and the anti-spam filtering feature is divided into two parts. The Front End server performs Connection Filtering and the Back End server does the Content Filtering (including the IMF filter – Exchange Intelligent Message Filter and the virus-detecting agent – Malware Agent).
All roles (except for Edge Transport) are merged in Exchange 2016, and Exchange 2016 has all these transport role services as well
And this article also indicates the steps to enable the agent you installed and restart the Front End Transport service.
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