Hey,
You should be able to use S2D as a shared storage for Failover Cluster. The following article might be helpful:
https://docs.aws.amazon.com/AWSEC2/latest/WindowsGuide/ec2-tutorial-s2d.html
As an alternative, StarWind VSAN can be used as a shared storage in AWS. The following quick start guide should help with configuration:
https://aws-quickstart.github.io/quickstart-starwind-vsan/
Might be helpful as well:
https://www.starwindsoftware.com/resource-library/starwind-virtual-san-aws-ec2-deployment-guide/
Cheers,
Alex Bykvoskyi
StarWind Software
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