Hi,
I’m not sure about the Intellimouse.
Some mice store settings in the Registry. Powershell could modify registry settings using Set-ItemProperty cmdlet, in which case the answer is yes.
Some mice use the ini file to store settings (basically in ProgramFiles\AppName). In this case, you could modify the .ini file (this is just a text file), using the power shell Replace operator.
Other than that, there is no official documentation for this
--If the reply is helpful, please Upvote and Accept as answer--