Hi There,
Thank you for asking this question on the Microsoft Q&A Platform.
Please provide more details here, like is this your production environment and are you facing any issue?
If this is your production environment and if you are facing any issue then I would suggest to take a downtime for this activity. Because you have to restart the secret server after the change. For lower environment you can take action accordingly.
Please have a look into MS Doc where it's clearly explained How to Change the Master Secret Server
Note :- On a system that supports User Account Control (UAC), you may need to run the tool with Administrative privileges.
Regards,
Kamlesh Kumar
BizTalk Techie
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