Hello @Mattia Fravezzi
Welcome to Microsoft Q&A Platform.
End-to-end (E2E) latency measures the interval from when Azure Storage receives the first packet of the request until Azure Storage receives a client acknowledgment on the last packet of the response.
There are many different factors that can be related, like operation size, client configuration, client CPU/memory or network path:
https://learn.microsoft.com/en-us/azure/storage/blobs/storage-blobs-latency#factors-influencing-latency
I would recommend checking the article below as starting point:
https://learn.microsoft.com/en-us/azure/storage/common/troubleshoot-latency-storage-analytics-logs
A network capture taken at the time of the issue should help, you can look for retransmits and high response times
If the issue requires remote assistance & collection of logs for further assistance, I request you file a support ticket if you have a support plan
I hope this helps!
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