1) Azure SQL Database is always using 100% memory by design.
2) Where else to look at?
The following query tells you which resource(s) consumption is(are) creating DTU spike:
SELECT
(COUNT(end_time) - SUM(CASE WHEN avg_cpu_percent > 80 THEN 1 ELSE 0 END) * 1.0) / COUNT(end_time) AS 'CPU Fit Percent'
,(COUNT(end_time) - SUM(CASE WHEN avg_log_write_percent > 80 THEN 1 ELSE 0 END) * 1.0) / COUNT(end_time) AS 'Log Write Fit Percent'
,(COUNT(end_time) - SUM(CASE WHEN avg_data_io_percent > 80 THEN 1 ELSE 0 END) * 1.0) / COUNT(end_time) AS 'Physical Data Read Fit Percent'
FROM sys.dm_db_resource_stats
If you change the aggregation types to max you may have a different perspective: