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If you used UWP WebView control to load your website, you could make webview control disable when load the specific uri. Listen webview NavigationStarting event and get current uri, and add constraint that load a blank page.
private async void TestWebView_NavigationStarting(WebView sender, WebViewNavigationStartingEventArgs args)
{
if (args.Uri !== your uri)
{
// do some stuff.
}
}