Hello.... I am having the exact same problem; mine just started over the weekend. All of our web servers are behaving as expected.
I think I know the problem, I just don't know how to fix it. (To be clear, we have been doing the following for about 10 years now, it just stopped working...)
This works: (where I always include the HOST NAME in the URL)
Request to: https://myserver.somewhere.com/mypage.html
This no longer works (but used to), when I make the request via IP Address and included the HTTP Header:
Request to: https://{IPAddress}/mypage.html using HTTP Header: myserver.somewhere.com (Hostname matches Binding on IIS server)
I am using another monitoring program as well, and it has NO PROBLEMS accessing the web server using IP address with the HTTP Header.
Yes, I get the correct IP address when I do an nslookup for myserver.somewhere.com. There are no network issues, the problem is isolated to SCOM 2019 doing a test.
Same results as Brian:
Any ideas?
It simply looks like SCOM is not sending the host header tag anymore. (The header tag is of course, quite important, as it tells IIS which web application to bind to.)