@Anindya Kumar Bhattacharjee Did you ever resolve this? I’m seeing the same behaviour
Smtp relay not working when new exchange 2019 servers are added to load balancer in exchange 2013 environment
Anonymous
Dedicated smtp relay receive connectors have been created on exchange 2019 servers. When the new servers are added to load balancer mail replay from applications fail.
Error: 5.7.54 smtp: unable to relay recipient in non-accepted domain.
Verified that ms-exch-smtp-accept-any-recipient extended rights is added to anonymous logon user.