Hi @KishoreChilaparapu-4663 Thank you for posting your question on Microsoft Q&A and for using Azure services.
My understanding is that you are asking ids it is possible to migrate 50TB of data from SQL server to SQL server on Azure vm. Please let me know if my understanding is not correct.
I would recommend using Azure Data Box in this scenario. Using DMS will take a lot of time.
Azure data Box
Regards,
Oury