Outlook issues

Question

I have 1 user who is having problems with Outlook.
Our environment is a hybrid setup with 1 on premises Exchange server which is just used as a transport server, all user mailboxes are Exchange online. All client machines are Windows 10 21H1 and our Office install is 365 for Business.

This user sees Outlook sit there saying it is gathering mailbox settings when he launches it until it is closed Close Outlook, start it in safe mode and try again and it works for a while. HOWEVER, other users logging on to this machine do NOT get the issue, if this user logs on to another machine, even a fresh out of the box, never used machine, he sees the same problem.
In addition, he is unable to open things like the Microsoft store, the native calculator app, Windows Defender...
Again, these issues follow him to a different machine, but only AFTER he has used Outlook, everything works just fine until he opens his email.

I've been doing this job a long time but never seen this before, anyone seen it and/or have a suggestion for resolving it?

Answer 1

Seems that Outlook does start in safe mode, I think the problem is likely with one of your add-ins. You'll need to disable all of your add-ins before restarting Outlook.
See: Disable add-ins

Answer 2

It seems to be an issue with the user account as he is unable to open things like the Microsoft store, the native calculator app, Windows Defender...