Hello @hao chen ,
Yes, you can detect mouse update and get update information via LastMouseUpdateTime.
For how does it work you can refer to this official sample: DXGIDesktopDuplication.
PtrInfo->LastTimeStamp = FrameInfo->LastMouseUpdateTime;
If the answer is helpful, please click "Accept Answer" and upvote it.
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.