Hi @Billy Blue ,
The issue might be that:
You're using an invalid certificate:
The certificate wasn't issued by a trustworthy authority.
Try to navigate to the service URL using a browser and have a check.
Here is a same thread you may take a reference to : https://social.technet.microsoft.com/Forums/msonline/en-US/f9aee5bb-d307-4782-9633-adc29fd10189/ssisssdt-the-underlying-connection-was-closed?forum=sqlintegrationservices
Regards,
Zoe Hui
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