Windows 10 Security
Windows 10: A Microsoft operating system that runs on personal computers and tablets.Security: The precautions taken to guard against crime, attack, sabotage, espionage, or another threat.
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I have configured Application Guard in Standalone mode. So no websites open in Application Guard by default.
However there is one http only (NOn-SSL) Website which opens in Application Guard Window.
I shall suggest you to go through the following Microsoft reference: