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GuidanceInference

Back to overview of RI Inferences

A guidance inference is tied to a finding inference (see finding inference.) The ACR (American College of Radiology) determines the guidelines for which findings a guidance is made. A guidance can include suppressors, which are aspects of the finding for which one or more values were found in the text, for example, a size. These suppressor values often overlap with the information in the finding. However, the code that generates the guidance sometimes identifies suppressors that aren't present in the finding.

  • Field kind is guidance.
  • Field finding is a finding inference. (see finding inference.)
  • Field identifier is a CodeableConcept containing either a SNOMED code or a RadLex code. This concept represents the type of the guidance. See Appendix A for the possible codes for identifier.
  • Field ranking has either value "high" or "low." It indicates how important the guidance is compared to other guidances in the document with the same identifier.
  • Field recommendationProposals, if filled, contains recommendation inferences. See recommendation inference. These recommendations are based on the information in finding and presentGuidanceInformation (see infra.) For a recommendation in this field, an image procedure's modality can be SNOMED code 266750002 ("NO FOLLOW-UP ARRANGED (FINDING)") which means that no follow-up procedure is needed. (This code doesn't occur for normal recommendation inferences outside of guidances.)
  • Field presentGuidanceInformation, if filled, contains one or more instances of PresentGuidanceInformation, each of which corresponds to a suppressor. See the next section.
  • Field missingGuidanceInformation, if filled, contains suppressor strings (the same kind of strings as in PresentGuidanceInformation.presentGuidanceItem, see the next section.) They're the suppressor strings for which no value is found, and for which the text would need to provide a value to enable the code to make a recommendation.
    Fields kind, finding, identifier, and ranking are mandatory.

Example of a guidance, without extensions and without the real contents of the finding field:

{
	"kind": "guidance",
	"finding": "<finding inference not shown>",
	"identifier": {
		"coding": [
			{
				"system": "http://radlex.org",
				"code": "RID50503",
				"display": "TI-RADS ASSESSMENT"
			}
		]
	},
	"presentGuidanceInformation": [
		{
			"presentGuidanceItem": "MAX DIAMETER",
			"sizes": [
				{
					"resourceType": "Observation",
					"component": [
						{
							"code": {
								"coding": [
									{
										"system": "http://radlex.org",
										"code": "246115007",
										"display": "SIZE (ATTRIBUTE)"
									}
								]
							},
							"valueQuantity": {
								"value": 5.0,
								"unit": "MILLIMETER"
							},
							"interpretation": [
								{
									"coding": [
										{
											"code": "15240007",
											"display": "CURRENT"
										}
									]
								}
							]
						}
					]
				}
			],
			"presentGuidanceValues": [
				"MAX DIAMETER"
			]
		},
		{
			"presentGuidanceItem": "SIZE",
			"sizes": [
				{
					"resourceType": "Observation",
					"component": [
						{
							"code": {
								"coding": [
									{
										"system": "http://radlex.org",
										"code": "246115007",
										"display": "SIZE (ATTRIBUTE)"
									}
								]
							},
							"valueQuantity": {
								"value": 5.0,
								"unit": "MILLIMETER"
							},
							"interpretation": [
								{
									"coding": [
										{
											"code": "15240007",
											"display": "CURRENT"
										}
									]
								}
							]
						}
					]
				}
			],
			"presentGuidanceValues": [
				"SIZE"
			]
		},
		{
			"presentGuidanceItem": "COMPOSITION",
			"presentGuidanceValues": [
				"CYSTIC OR ALMOST COMPLETELY CYSTIC"
			]
		},
		{
			"presentGuidanceItem": "SOLITARY OR MULTIPLE",
			"presentGuidanceValues": [
				"MULTIPLE"
			]
		}
	],
	"ranking": "high",
	"missingGuidanceInformation": [
		"ECHOGENICITY",
		"SHAPE",
		"MARGIN",
		"ECHOGENIC FOCI"
	]
}

PresentGuidanceInformation

Field presentGuidanceItem is a String that represents a kind of information, for example, "SIDE" or "SIZE."
Field presentGuidanceValues, if filled, contain one or more value Strings. For example, for presentGuidanceItem "SIDE" it could be "LEFT" or "RIGHT."
Field sizes is filled if the presentGuidanceItem refers to a size. It contains an array of FHIR.R4. Observation, but this array has at most one element. This Observation element then has the sizes information in its components, in the same format as for findings. See finding inference.
Field maximumDiameterAsInText is filled if the presentGuidanceItem refers to a maximum diameter. Fields value and unit should be set.
Only field presentGuidanceItem is mandatory, but one of the other three fields should also be filled.

Appendix A: possible codes for field "identifier"

System Code Display
SNOMED 445039006 MASS OF UTERINE ADNEXA (FINDING)
SNOMED 237783006 MASS OF ADRENAL GLAND (FINDING)
SNOMED 39400004 INJURY OF LIVER (DISORDER)
SNOMED 300331000 LESION OF LIVER (FINDING)
SNOMED 363358000 MALIGNANT TUMOR OF LUNG (DISORDER)
SNOMED 61823004 INJURY OF PANCREAS (DISORDER)
SNOMED 79131000119100 KIDNEY LESION (FINDING)
SNOMED 23589004 INJURY OF SPLEEN (DISORDER)
SNOMED 40095003 INJURY OF KIDNEY (DISORDER)
SNOMED 237495005 THYROID NODULE (DISORDER)
SNOMED 233985008 ABDOMINAL AORTIC ANEURYSM (DISORDER)
SNOMED 858901000000108 PREGNANCY OF UNKNOWN LOCATION (DISORDER)
SNOMED 289208006 FINDING OF VIABILITY OF PREGNANCY (FINDING)
SNOMED 363351006 MALIGNANT TUMOR OF RECTUM (DISORDER)
SNOMED 364327007 VIABILITY OF PREGNANCY (OBSERVABLE ENTITY)
SNOMED 97171000119100 CYST OF UTERINE ADNEXA (DISORDER)
SNOMED 31258000 CYST OF PANCREAS (DISORDER)
SNOMED 276650005 PERINATAL SUBEPENDYMAL HEMORRHAGE (DISORDER)
SNOMED 300346007 LESION OF GALLBLADDER (FINDING)
SNOMED 399244003 DISORDER OF PITUITARY GLAND (DISORDER)
SNOMED 289840004 LESION OF OVARY (FINDING)
RADLEX RID50149 PULMONARY NODULE
RADLEX RID50503 TI-RADS ASSESSMENT
RADLEX RID50134 LUNG-RADS ASSESSMENT

Appendix B: Overview of supported guidance inferences grouped by guideline

ACR Appropriateness Criteria
These guidelines assist healthcare providers in making the most appropriate imaging or treatment decisions for specific clinical conditions:
https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Appropriateness-Criteria

Guidance SNOMED/RADLEX Code White paper reference
Abdominal Aortic Aneurysm* SNOMED 233985008 Khosa, F., Krinsky, G., Macari, M., Yucel, E. K., & Berland, L. L. (2013). Managing Incidental Findings on Abdominal and Pelvic CT and MRI, Part 2: White Paper of the ACR Incidental Findings Committee II on Vascular Findings. Journal of the American College of Radiology, 10(10), 789-794. doi: 10.1016/j.jacr.2013.05.021
Gallbladder and Biliary tract* SNOMED 300346007 Sebastian, S., Araujo, C., Neitlich, J. D., & Berland, L. L. (2013). Managing Incidental Findings on Abdominal and Pelvic CT and MRI, Part 4: White Paper of the ACR Incidental Findings Committee II on Gallbladder and Biliary Findings. Journal of the American College of Radiology, 10(12), 953-956. doi: 10.1016/j.jacr.2013.05.022
Germinal Matrix Hemorrhage* SNOMED 276650005 Bowerman RA, Donn SM, Silver TM, Jaffe MH. Natural History of Neonatal Periventricular/Intraventricular Hemorrhage and Its Complications: Sonographic Observations. AJNR Am J Neuroradiol. 1984;5(5):527-538; Brouwer AJ, Groenendaal F, Benders MJNL, de Vries LS. Early and late complications of germinal matrix hemorrhage-intraventricular hemorrhage in the preterm infant: what is new? Neonatology. 2014;106(4):296-303. doi: 10.1159/000365127
Lung Cancer Staging SNOMED 363358000 Amin MB, Edge SB, Greene FL, et al. AJCC Cancer Staging Manual, 8th Edition. Switzerland: Springer; 2017:431-455
Pregnancy Location* SNOMED 858901000000108 Doubilet PM, Benson CB, Bourne T, Blaivas M. Diagnostic Criteria for Nonviable Pregnancy Early in the First Trimester. N Engl J Med. 2013;369(15):1443-1451. doi: 10.1056/NEJMra1302417
Pregnancy Viability Initial* SNOMED 289208006 Doubilet PM, Benson CB, Bourne T, Blaivas M. Diagnostic Criteria for Nonviable Pregnancy Early in the First Trimester. N Engl J Med. 2013;369(15):1443-1451. doi: 10.1056/NEJMra1302417
Pregnancy Viability Follow-up* SNOMED 364327007 Doubilet PM, Benson CB, Bourne T, Blaivas M. Diagnostic Criteria for Nonviable Pregnancy Early in the First Trimester. N Engl J Med. 2013;369(15):1443-1451. doi: 10.1056/NEJMra1302417
Rectal Cancer Staging SNOMED 363351006 Al-Sukhni E, Milot L, Fruitman M, Brown G, Schmocker S, Kennedy E. User’s Guide for the Synoptic MRI Report for Pre-Operative Staging of Rectal Cancer. Cancer Care Ontario; 2015.

ACR Incidental Findings
These guidelines provide recommendations for managing incidental findings discovered during imaging studies performed for unrelated reasons:
https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Incidental-Findings

Guidance SNOMED/RADLEX Code White paper reference
Adnexal cyst* SNOMED 97171000119100 Levine D, Brown DL, Andreotti RF, et al. Recommendations for adnexal cyst follow-up per Society of Radiologists in Ultrasound 2009 consensus statement on management of asymptomatic ovarian and other adnexal cysts. Radiology. 2010;256(3):943-954. doi: 10.1148/radiol.10100213
Adnexal mass* SNOMED 445039006 Patel MD, Ascher SM, Paspulati RM, Shanbhogue AK, Siegelman ES, Stein MW, Berland LL. Managing Incidental Findings on Abdominal and Pelvic CT and MRI, Part 1: White Paper of the ACR Incidental Findings Committee II on Adnexal Findings. J Am Coll Radiol. 2013;10(9):675-681. doi: 10.1016/j.jacr.2013.05.023
Adrenal nodule* SNOMED 237783006 Mayo-Smith WW, Song JH, Boland GL, et al. Management of Incidental Adrenal Masses: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2017;14(8):1038-1044. doi: 10.1016/j.jacr.2017.05.001
Liver lesion* SNOMED 300331000 Berland LL, Silverman SG, Gore RM, et al. Managing Incidental Findings on Abdominal CT: White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2010;7(10):754-773. doi: 10.1016/j.jacr.2010.06.013
Pancreatic cyst* SNOMED 31258000 Megibow AJ, Baker ME, Morgan DE, et al. Management of Incidental Pancreatic Cysts: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2017;14(8):911-923. doi: 10.1016/j.jacr.2017.05.001
Pituitary* SNOMED 399244003 Hoang JK, Hoffman AR, González RG, et al. Management of Incidental Pituitary Findings on CT, MRI, and 18F-Fluorodeoxyglucose PET: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2018;15(7):966-972. doi: 10.1016/j.jacr.2018.03.037
Renal lesion* SNOMED 79131000119100 Herts BR, Silverman SG, Hindman NM, et al. Management of the Incidental Renal Mass on CT: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2018;15(2):264-273. doi: 10.1016/j.jacr.2017.05.001
Thyroid nodule* SNOMED 237495005 Hoang JK, Langer JE, Middleton WD, et al. Managing incidental thyroid nodules detected on imaging: white paper of the ACR Incidental Thyroid Findings Committee. J Am Coll Radiol. 2015;12(2):143-150. doi: 10.1016/j.jacr.2014.09.038

RADS (Reporting and Data Systems)
Reporting and Data Systems are standardized systems for reporting and data management in radiology, focusing on specific conditions and imaging modalities:
https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Reporting-and-Data-Systems

Guidance SNOMED/RADLEX Code White paper reference
Lung-RADS RADLEX RID50134 Kazerooni EA, Austin JHM, Black WC, et al. ACR-STR Practice Parameter for the Performance and Reporting of Lung Cancer Screening Thoracic Computed Tomography (Resolution 4). J Thorac Imaging. 2014;29(5):310-316. doi: 10.1097/RTI.0000000000000097
TI-RADS* RADLEX RID50503 Tessler FN, Middleton WD, Grant EG, et al. White Paper of the ACR TI-RADS Committee. J Am Coll Radiol. 2017;14(5):587-595. doi: 10.1016/j.jacr.2017.01.046

Trauma and Injury Grading (American Association for the Surgery of Trauma (AAST))
These guidelines provide standardized grading systems for assessing the severity of injuries: https://www.aast.org/resources-detail/injury-scoring-scale

Guidance SNOMED/RADLEX Code White paper reference
Hepatic trauma SNOMED 39400004 Tinkoff G, Esposito TJ, Reed J, et al. American Association for the Surgery of Trauma Organ Injury Scale I: Spleen, Liver, and Kidney, Validation Based on the National Trauma Data Bank. J Trauma. 2008;64(2):204-210. doi: 10.1097/TA.0b013e31815b847a
Pancreatic Injury Grading SNOMED 61823004 Tinkoff G, Esposito TJ, Reed J, et al. American Association for the Surgery of Trauma Organ Injury Scale I: Spleen, Liver, and Kidney, Validation Based on the National Trauma Data Bank. J Trauma. 2008;64(2):204-210. doi: 10.1097/TA.0b013e31815b847a
Renal Injury Grading SNOMED 40095003 Tinkoff G, Esposito TJ, Reed J, et al. American Association for the Surgery of Trauma Organ Injury Scale I: Spleen, Liver, and Kidney, Validation Based on the National Trauma Data Bank. J Trauma. 2008;64(2):204-210. doi: 10.1097/TA.0b013e31815b847a
Splenic Injury Grading SNOMED 23589004 Tinkoff G, Esposito TJ, Reed J, et al. American Association for the Surgery of Trauma Organ Injury Scale I: Spleen, Liver, and Kidney, Validation Based on the National Trauma Data Bank. J Trauma. 2008;64(2):204-210. doi: 10.1097/TA.0b013e31815b847a

Fleischner society guidelines

Guidance SNOMED/RADLEX Code White paper reference
Pulmonary nodule* RADLEX RID50149 MacMahon H, Naidich D, Goo J et al. Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017. Radiology. 2017;284(1):228-43. doi: 10.1148/radiol.2017161659 - PubMed

* RecommendationProposal is applicable

Examples Request/Response JSON:

{
  "jobData" : {
    "configuration" : {
      "inferenceOptions" : {
        "followupRecommendationOptions" : {
          "includeRecommendationsWithNoSpecifiedModality" : false,
          "includeRecommendationsInReferences" : false,
          "provideFocusedSentenceEvidence" : true
        },
        "findingOptions" : {
          "provideFocusedSentenceEvidence" : true
        },
        "GuidanceOptions" : {
          "showGuidanceInHistory" : true
        }
      },
      "inferenceTypes" : ["guidance" ],
      "locale" : "en-US",
      "verbose" : false,
      "includeEvidence" : false
    },
    "patients" : [ {
      "id" : "11111",
      "details" : {
        "sex" : "female",
        "birthDate" : "1939-05-25",
        "clinicalInfo" : [ {
          "resourceType" : "Observation",
          "status" : "unknown",
          "code" : {
            "coding" : [ {
              "system" : "http://www.nlm.nih.gov/research/umls",
              "code" : "C0018802",
              "display" : "MalignantNeoplasms"
            } ]
          },
          "valueBoolean" : "true"
        } ]
      },
      "encounters" : [ {
        "id" : "encounterid1",
        "period" : {
          "start" : "2014-2-20T00:00:00",
          "end" : "2014-2-20T00:00:00"
        },
        "class" : "inpatient"
      } ],
      "patientDocuments" : [ {
        "type" : "note",
        "clinicalType" : "radiologyReport",
        "id" : "docid1",
        "language" : "en",
        "authors" : [ {
          "id" : "authorid1",
          "name" : "authorname1"
        } ],
        "specialtyType" : "radiology",
        "createdAt" : "2014-2-20T00:00:00",
        "administrativeMetadata" : {
          "orderedProcedures" : [ {
            "code" : {
              "coding" : [ {
                "system" : "http://loinc.org",
                "code" : "CTCHWO",
                "display" : "CT CHEST WO CONTRAST    "
              } ]
            },
            "description" : "CT CHEST WO CONTRAST    "
          } ],
          "encounterId" : "encounterid1"
        },
        "content" : {
          "sourceType" : "inline",
          "value" : "\n\n\n\r\n\nEXAM: CT CHEST WO CONTRAST\n\nINDICATION: abnormal lung findings. History of emphysema.\n\nTECHNIQUE: Helical CT images through the chest, without contrast. This exam was performed using one or more of the following dose reduction techniques: Automated exposure control, adjustment of the mA and/or kV according to patient size, and/or use of iterative reconstruction technique. \n\nCOMPARISON: Chest CT dated 6/21/2022.\n\nNumber of previous CT examinations or cardiac nuclear medicine (myocardial perfusion) examinations performed in the preceding 12-months: 2\n\nFINDINGS: \n\nHeart size is normal. No pericardial effusion. Thoracic aorta as well as pulmonary arteries are normal in caliber. There are dense coronary artery calcifications. No enlarged axillary, mediastinal, or hilar lymph nodes by CT size criteria. Central airways are widely patent. No bronchial wall thickening. No pneumothorax, pleural effusion or pulmonary edema. The previously identified posterior right upper lobe nodules are no longer seen. However, there are multiple new small pulmonary nodules. An 8 mm nodule in the right upper lobe, image #15 series 4. New posterior right upper lobe nodule measuring 6 mm, image #28 series 4. New 1.2 cm pulmonary nodule, right upper lobe, image #33 series 4. New 4 mm pulmonary nodule left upper lobe, image #22 series 4. New 8 mm pulmonary nodule in the left upper lobe adjacent to the fissure, image #42 series 4. A few new tiny 2 to 3 mm pulmonary nodules are also noted in the left lower lobe. As before there is a background of severe emphysema. No evidence of pneumonia.\n\nLimited evaluation of the upper abdomen shows no concerning abnormality.\n\nReview of bone windows shows no aggressive appearing osseous lesions.\n\n\nIMPRESSION:\n\n1. Previously identified small pulmonary nodules in the right upper lobe have resolved, but there are multiple new small nodules scattered throughout both lungs. Recommend short-term follow-up with noncontrast chest CT in 3 months as per current  Current guidelines (2017 Fleischner Society).\n2. Severe emphysema.\n\nFindings communicated to Dr. Jane Smith.\n\n\r\n"
        }
      } ]
    } ]
  }
}
{
  "result": {
    "patientResults": [
      {
        "patientId": "11111",
        "inferences": [
          {
            "kind": "guidance",
            "finding": {
              "kind": "finding",
              "finding": {
                "resourceType": "Observation",
                "id": "3781",
                "status": "unknown",
                "code": {
                  "coding": [
                    {
                      "system": "http://snomed.info/sct",
                      "code": "404684003",
                      "display": "CLINICAL FINDING (FINDING)"
                    }
                  ]
                },
                "interpretation": [
                  {
                    "coding": [
                      {
                        "system": "http://snomed.info/sct",
                        "code": "7147002",
                        "display": "NEW (QUALIFIER VALUE)"
                      }
                    ]
                  }
                ],
                "component": [
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "131195008",
                          "display": "SUBJECT OF INFORMATION (ATTRIBUTE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "27925004",
                          "display": "NODULE (MORPHOLOGIC ABNORMALITY)"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "722871000000108",
                          "display": "ANATOMY (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "39607008",
                          "display": "LUNG STRUCTURE (BODY STRUCTURE)"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "722871000000108",
                          "display": "ANATOMY (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://radlex.org",
                          "code": "RID1301",
                          "display": "LUNG"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "722871000000108",
                          "display": "ANATOMY (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://radlex.org",
                          "code": "RID13437",
                          "display": "LUNGS"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "723851000000107",
                          "display": "GUIDANCE (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://radlex.org",
                          "code": "RID50149",
                          "display": "PULMONARY NODULE"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "362981000",
                          "display": "QUALIFIER VALUE (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "703248002",
                          "display": "APPEARANCE (OBSERVABLE ENTITY)"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "46150521",
                          "display": "MULTIPLE (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueBoolean": true
                  }
                ]
              },
              "extension": [
                {
                  "extension": [
                    {
                      "url": "code",
                      "valueString": "18782-3"
                    },
                    {
                      "url": "codingSystem",
                      "valueString": "2.16.840.1.113883.6.1"
                    },
                    {
                      "url": "codingSystemName",
                      "valueString": "http://loinc.org"
                    },
                    {
                      "url": "displayName",
                      "valueString": "RADIOLOGY STUDY OBSERVATION (NARRATIVE)"
                    }
                  ],
                  "url": "section"
                }
              ]
            },
            "identifier": {
              "coding": [
                {
                  "system": "http://radlex.org",
                  "code": "RID50149",
                  "display": "PULMONARY NODULE"
                }
              ]
            },
            "ranking": "low",
            "missingGuidanceInformation": [
              "SIZE"
            ]
          },
          {
            "kind": "guidance",
            "finding": {
              "kind": "finding",
              "finding": {
                "resourceType": "Observation",
                "id": "3782",
                "status": "unknown",
                "code": {
                  "coding": [
                    {
                      "system": "http://snomed.info/sct",
                      "code": "404684003",
                      "display": "CLINICAL FINDING (FINDING)"
                    }
                  ]
                },
                "component": [
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "131195008",
                          "display": "SUBJECT OF INFORMATION (ATTRIBUTE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "27925004",
                          "display": "NODULE (MORPHOLOGIC ABNORMALITY)"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "722871000000108",
                          "display": "ANATOMY (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "39607008",
                          "display": "LUNG STRUCTURE (BODY STRUCTURE)"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
                      "coding": [
                        {
                          "system": "http://snomed.info/sct",
                          "code": "722871000000108",
                          "display": "ANATOMY (QUALIFIER VALUE)"
                        }
                      ]
                    },
                    "valueCodeableConcept": {
                      "coding": [
                        {
                          "system": "http://radlex.org",
                          "code": "RID13406",
                          "display": "ANATOMICAL LOBE"
                        }
                      ]
                    }
                  },
                  {
                    "code": {
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                        {
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