A family of Microsoft presentation graphics products that offer tools for creating presentations and adding graphic effects like multimedia objects and special effects with text.
We're able to replicate your issue on PowerPoint, kindly check if you can follow the steps below:
- Click on View tab on PowerPoint.
- Click on Notes Page.
- Check the pages that is not aligned properly on the page.
- Click on the slide and frame with circles will appear, which you can drag to adjust. 
- Point your mouse over the small circles and drag the slide to its appropriate size. 
- A dashed line will appear once you've adjust the slide to its proper position. 
- You can also click on the center of the slide and adjust its position. 
Update us with the outcome so we can provide you further assistance.