Hi,
It’s supported to use BitLocker encryption on file server. You can refer to BitLocker: How to deploy on Windows Server 2012 and later to deploy.
But you need to check whether the server has a TPM chipset version 1.2 or higher. If it doesn’t have, you need to check Allow BitLocker without a compatible TPM in Computer Configuration/Administrative Templates/Windows Components/BitLocker Drive Encryption/Operating System Drives/Require additional authentication at startup in Group Policy Editor.
After you enable BitLocker, users cannot access the shared files unless the partition where the files are stored is decrypted.
Please keep your recovery key safe. If possible, make several copies and save them properly. They are critical to your data recovery if an incident happens.
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