Hi @Peter_1985 ,
If you want to prevent malware from infecting your windows server 2016, windows Defender AV is malware protection that immediately and actively protects Windows Server 2016 against known malware and can regularly update antimalware definitions through Windows Update.
For your reference:
Windows Defender Antivirus for Windows Server
Best Regards,
Candy
--------------------------------------------------------------
If the Answer is helpful, please click "Accept Answer" and upvote it.
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.