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Hi @Chakaravarthi Rangarajan Bhargavi Welcome to Microsoft Q&A thanks for posting your question.
Yes, you can connect PowerApps with relational databases like Oracle and SQL Server The choice of database will depend on your specific requirements and preferences
Here are the reference document you can find below
https://learn.microsoft.com/en-us/power-apps/maker/canvas-apps/connections/connection-oracledb
I would also suggest you post your question in PowerApps Community for additional information.
Here is the community link: https://powerusers.microsoft.com/t5/Power-Apps-Community/ct-p/PowerApps1
I hope this information helps
Regards
Geetha