Hello @Paul Lapierre ,
Thank you for posting here.
To better understand your question, please confirm the following information at your convenience.
1.Is your AD forest single forest and single domain environment or single forest and multiple domains environment?
2.If your AD forest is single forest and multiple domains environment. How many domains are there in your AD forest?
For example:

3.How many DCs are there in each domain? Please run nltest /dclist:domain.com to check.
4.Based on the description "when I try to disable his admin account active directory replication fails.", do you mean enable his admin account active directory replication works fine?
5.Is your account a domain administrator account or a member of the domain administrator group?
Please check AD replication status before disabling his admin account and after disabling his admin account, run the following commands on PDC to check.
repadmin /syncall /AdeP C:\rep1.txt
repadmin /showrepl C:\rep2.txt
repadmin /replsum C:\rep3.txt
repadmin /showrepl * /csv >c:\repsum.csv
Tip: Please do not upload these log files, because private information may be involved. If you confirm that the command result has error information, please provide us with part of the error code and error information (if private information is involved, please obfuscate).
Hope the information above is helpful.
Should you have any question or concern, please feel free to let us know.
Best Regards,
Daisy Zhou
============================================
If the Answer is helpful, please click "Accept Answer" and upvote it.